Description

5-Bromo-4-Fluoro-2-Methyl-7-Azaindole is a high-purity, multi-functional heterocyclic building block of significant importance in modern synthetic chemistry. Its value lies in its unique halogenated azaindole scaffold, which serves as a privileged structure for designing novel bioactive molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, drug discovery, and the synthesis of advanced intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of kinase inhibitors, particularly in oncology research targeting specific protein families.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization campaigns due to its modifiable halogen and methyl groups.
• Agrochemical Research: Serves as a precursor in the development of new herbicides and fungicides, leveraging the biological activity of the azaindole core.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and custom synthesis houses to produce complex, tailored molecules for clients.
• Academic Research: Used in universities and research institutes for methodological development in heterocyclic and cross-coupling chemistry.

Basic Information

Product Name	5-Bromo-4-Fluoro-2-Methyl-7-Azaindole
CAS No.	1352398-35-6
Molecular Formula	C8H6BrFN2
Molecular Weight	229.05 g/mol
Synonyms	5-Bromo-4-fluoro-2-methyl-1H-pyrrolo[2,3-b]pyridine; 4-Fluoro-5-bromo-2-methyl-7-azaindole; 2-Methyl-5-bromo-4-fluoro-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 5-bromo-4-fluoro-2-methyl-; 7-Azaindole, 5-bromo-4-fluoro-2-methyl-; 5-Br-4-F-2-Me-7-azaindole
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Fluoro-2-Methyl-7-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency, meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be stored away from light exposure. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.