Description

7-Amino-5-Fluoro-1H-Indazole is a high-purity fluorinated indazole derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular scaffold, which is essential for constructing complex molecules with targeted biological activity. This intermediate is primarily needed by pharmaceutical R&D and fine chemical manufacturers developing novel active pharmaceutical ingredients (APIs), particularly in oncology and CNS therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors and other small-molecule drug candidates.
• Agrochemical Research: Used in the synthesis of novel herbicides and pesticides leveraging its heterocyclic core.
• Material Science: Serves as a precursor for specialty polymers and advanced organic electronic materials.
• Bioconjugation & Probe Development: Utilized in creating fluorescent probes and biochemical tools due to its reactive amino group.
• Academic & Contract Research: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies.

Basic Information

Item	Details
Product Name	7-Amino-5-Fluoro-1H-Indazole
CAS No.	1352397-94-4
Molecular Formula	C7H6FN3
Molecular Weight	151.14 g/mol
Synonyms	5-Fluoro-1H-indazol-7-amine; 5-Fluoro-7-aminoindazole; 7-Amino-5-fluoroindazole; 1H-Indazole-7-amine, 5-fluoro-; 1352397-94-4; 5-Fluoro-1H-indazol-7-ylamine; 7-Amino-5-fluoro-1H-indazole
EINECS	Contact for details

Quality Control

Our 7-Amino-5-Fluoro-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting HPLC purity, NMR confirmation, and residual solvent levels are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.