Description

7-Bromo-3-Fluoro-5-Azaindole is a high-value, multi-functional heterocyclic building block essential for modern pharmaceutical and agrochemical research. This compound is specifically engineered to introduce both bromine and fluorine substituents onto the azaindole scaffold, enabling precise modulation of biological activity and physicochemical properties in target molecules. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical industry for the synthesis of novel drug candidates, particularly in kinase inhibitor and oncology research programs.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, receptor antagonists, and other small-molecule therapeutics, especially in oncology and CNS disorders.
• Agrochemical Research: Serves as a versatile scaffold for creating novel active ingredients with enhanced efficacy and environmental profiles.
• Chemical Biology Probe Development: Used to synthesize molecular probes for studying enzyme function and biological pathways.
• Material Science: Potential precursor for advanced organic electronic materials and functional polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services.
• Academic Research: Employed in university and institutional labs for methodological studies in heterocyclic and fluoroorganic chemistry.

Basic Information

Product Name	7-Bromo-3-Fluoro-5-Azaindole
CAS No.	1352397-80-8
Molecular Formula	C7H4BrFN2
Molecular Weight	215.02 g/mol
Synonyms	7-Bromo-3-fluoro-1H-pyrrolo[2,3-b]pyridine; 3-Fluoro-7-bromo-1H-pyrrolo[2,3-b]pyridine; 3-Fluoro-7-bromo-5-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 7-bromo-3-fluoro-; 7-Bromo-3-fluoro-1H-7-azaindole; 7-Br-3-F-5-AI
EINECS	Contact for details

Quality Control

Our 7-Bromo-3-Fluoro-5-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.