Description

6-Chloro-3-Fluoro-7-Azaindole is a high-purity, heterocyclic aromatic building block of significant interest in advanced organic synthesis. This compound matters as a privileged scaffold for constructing complex molecules, particularly in the pharmaceutical and agrochemical discovery pipelines. It is primarily needed by research chemists and process development scientists working on kinase inhibitors, receptor modulators, and other bioactive small molecules. The precise substitution pattern offers a versatile handle for further functionalization and structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially targeted therapies.
• Kinase Inhibitor Scaffold: Core structure for developing potent and selective inhibitors for various kinase targets.
• Agrochemical Research: Building block for creating new active ingredients with herbicidal or insecticidal properties.
• Chemical Biology Probes: Used in the design of molecular probes to study enzyme function and cellular pathways.
• Material Science: Potential monomer or precursor for specialty polymers and organic electronic materials.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and scale-up services.

Basic Information

Product Name	6-Chloro-3-Fluoro-7-Azaindole
CAS No.	1352395-89-1
Molecular Formula	C7H4ClFN2
Molecular Weight	170.57 g/mol
Synonyms	6-Chloro-3-fluoro-1H-pyrrolo[2,3-b]pyridine; 3-Fluoro-6-chloro-1H-pyrrolo[2,3-b]pyridine; 6-Chloro-3-fluoro-7-azaindole; 3-Fluoro-6-chloro-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 6-chloro-3-fluoro-; 6-Chloro-3-fluoro-1H-7-azaindole
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-Fluoro-7-Azaindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity building blocks for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.