Description

1-Oxo-1,2,3,4-Tetrahydroisoquinoline-7-Carbonitrile is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry research and development. It is primarily sought by pharmaceutical companies and research institutions engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Employed in the construction of complex nitrogen-containing heterocycles due to its reactive nitrile and carbonyl functionalities.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for the study of organic reaction mechanisms and the development of new synthetic methodologies.

Basic Information

Product Name	1-Oxo-1,2,3,4-Tetrahydroisoquinoline-7-Carbonitrile
CAS No.	1352394-88-7
Molecular Formula	C₁₀H₈N₂O
Molecular Weight	172.18 g/mol
Synonyms	7-Cyano-1,2,3,4-tetrahydroisoquinolin-1-one; 7-Cyano-3,4-dihydro-1(2H)-isoquinolinone; 1,2,3,4-Tetrahydro-1-oxoisoquinoline-7-carbonitrile; 1-Oxo-1,2,3,4-tetrahydro-7-isoquinolinecarbonitrile; 7-Cyano-1-oxo-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydroisoquinoline-7-carbonitrile-1-one
EINECS	Contact for details

Quality Control

Our 1-Oxo-1,2,3,4-Tetrahydroisoquinoline-7-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.