Description

5-Amino-3-Fluoro-7-Azaindole is a high-value, multi-functional heterocyclic building block essential for modern synthetic chemistry. This compound is prized for its unique molecular architecture, which combines a reactive amino group with a fluorine substituent on an azaindole scaffold, enabling precise structural modifications. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used to construct novel heterocyclic scaffolds for the development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Serves as a building block for creating organic electronic materials, such as charge-transport layers or fluorescent dyes.
• Chemical Biology: Employed as a probe or tag in medicinal chemistry for structure-activity relationship (SAR) studies and bio-conjugation.
• Academic & Contract Research: A valuable reagent for methodological development in organic synthesis and heterocyclic chemistry at research institutions and CROs.

Basic Information

Product Name	5-Amino-3-Fluoro-7-Azaindole
CAS No.	1352394-81-0
Molecular Formula	C7H6FN3
Molecular Weight	151.14 g/mol
Synonyms	3-Fluoro-1H-pyrrolo[2,3-b]pyridin-5-amine; 5-Amino-3-fluoro-1H-pyrrolo[2,3-b]pyridine; 3-Fluoro-5-amino-7-azaindole; 5-Amino-3-fluoro-7-aza-indole; 1H-Pyrrolo[2,3-b]pyridin-5-amine, 3-fluoro-
EINECS	Contact for details

Quality Control

Our 5-Amino-3-Fluoro-7-Azaindole is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.