Description

7-Amino-5-Fluoroindole is a high-purity fluorinated indole derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino and a fluorine substituent, makes it a versatile intermediate for creating complex molecules with tailored properties. This compound is essential for research and development in the pharmaceutical and agrochemical industries, particularly in the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, including kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Research: Used to develop novel pesticides and herbicides, where the fluorine atom can enhance metabolic stability and bioavailability.
• Material Science: Building block for creating specialized fluorinated polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Versatile reagent for constructing complex heterocyclic frameworks in medicinal and process chemistry.
• Bioconjugation & Probe Development: Useful in creating fluorescent probes and biochemical tools due to the reactive amino group.

Basic Information

Product Name	7-Amino-5-Fluoroindole
CAS No.	1352394-08-1
Molecular Formula	C8H7FN2
Molecular Weight	150.15 g/mol
Synonyms	5-Fluoro-1H-indol-7-amine; 5-Fluoro-7-aminoindole; 1H-Indol-7-amine, 5-fluoro-; 7-Amino-5-fluoro-1H-indole; 5-Fluoroindol-7-ylamine
EINECS	Contact for details

Quality Control

Our 7-Amino-5-Fluoroindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light brown powder or crystals
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.