Description

7-Fluoro-5-Hydroxyindazole is a high-purity fluorinated indazole derivative, a crucial building block in modern pharmaceutical and agrochemical research. Its value lies in its unique molecular scaffold, which combines a fluorine atom and a hydroxyl group on the indazole core, enabling precise modulation of biological activity and physicochemical properties. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, receptor antagonists, and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides and fungicides, leveraging the fluorine atom for enhanced bioavailability and stability.
• Chemical Biology Probe: Serves as a core structure for developing fluorescent tags or activity-based probes to study enzyme function.
• Material Science Precursor: Potential use in the synthesis of advanced organic materials, such as ligands for metal-organic frameworks (MOFs) or electronic materials.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and contract research organizations (CROs) exploring new heterocyclic chemistry.

Basic Information

Product Name	7-Fluoro-5-Hydroxyindazole
CAS No.	1352393-98-6
Molecular Formula	C7H5FN2O
Molecular Weight	152.13 g/mol
Synonyms	5-Hydroxy-7-fluoro-1H-indazole; 7-Fluoro-1H-indazol-5-ol; 1H-Indazol-5-ol, 7-fluoro-; 7-Fluoro-5-indazolol; 1352393-98-6; 7-Fluoroindazol-5-ol; 5-Hydroxy-7-fluoroindazole; 7-F-5-OH-indazole
EINECS	Contact for details

Quality Control

Our 7-Fluoro-5-Hydroxyindazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and KF titration for moisture content, to ensure compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.