Description

Methyl 4-Bromo-3-Chloro-Indole-6-Carboxylate is a high-purity, multi-functional indole derivative serving as a critical building block in advanced organic synthesis. Its value lies in its precise halogen substitution pattern, which enables targeted molecular construction for complex heterocyclic systems. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potent, biologically active indole-based compounds for drug discovery programs.
• Agrochemical Research: Used to construct novel fungicides, herbicides, or plant growth regulators leveraging the indole scaffold.
• Material Science: Serves as a monomer or functional unit in the development of specialty polymers and organic electronic materials.
• Chemical Biology: Employed as a probe or labeling reagent due to its reactive halogen sites for bioconjugation.
• Academic & Contract Research: Fundamental building block for methodological studies in cross-coupling reactions and heterocyclic chemistry.

Basic Information

Product Name	Methyl 4-Bromo-3-Chloro-Indole-6-Carboxylate
CAS No.	1352393-64-6
Molecular Formula	C10H7BrClNO2
Molecular Weight	288.52 g/mol
Synonyms	Methyl 4-bromo-3-chloro-1H-indole-6-carboxylate; 6-Carbomethoxy-4-bromo-3-chloroindole; 4-Bromo-3-chloro-indole-6-carboxylic acid methyl ester; 1H-Indole-6-carboxylic acid, 4-bromo-3-chloro-, methyl ester; MBrCIC; Methyl 4-Br-3-Cl-indole-6-COOMe
EINECS	Contact for details

Quality Control

Every batch of Methyl 4-Bromo-3-Chloro-Indole-6-Carboxylate is produced and tested under a strict quality management system to ensure consistency and reliability for your synthetic workflows. Our standard grade typically meets a purity specification of ≥97% (HPLC), with comprehensive identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.