Description

1(2H)-Isoquinolinone,6,7-Difluoro-3,4-Dihydro- is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials, where its unique difluoro-substituted isoquinolinone core enables precise modulation of biological activity and physicochemical properties. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries focused on creating next-generation fluorinated compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in oncology, CNS disorders, and anti-infective therapies.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and pesticides, leveraging the fluorine atoms to enhance bioavailability and environmental stability.
• Material Science: Serves as a building block for creating specialized fluorinated polymers, liquid crystals, or organic electronic materials.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses serving the pharmaceutical and biotechnology sectors.

Basic Information

Product Name	1(2H)-Isoquinolinone,6,7-Difluoro-3,4-Dihydro-
CAS No.	1352393-61-3
Molecular Formula	C9H7F2NO
Molecular Weight	183.16 g/mol
Synonyms	6,7-Difluoro-3,4-dihydro-1(2H)-isoquinolinone; 6,7-Difluoro-1,2,3,4-tetrahydroisoquinolin-1-one; 6,7-Difluoro-3,4-dihydroisoquinolin-1(2H)-one; 6,7-Difluoro-1-oxo-1,2,3,4-tetrahydroisoquinoline; 1(2H)-Isoquinolinone, 6,7-difluoro-3,4-dihydro-; 6,7-Difluoro-1,2,3,4-tetrahydro-1-isoquinolinone
EINECS	Contact for details

Quality Control

Our 1(2H)-Isoquinolinone,6,7-Difluoro-3,4-Dihydro- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.