Description

1H-Pyrrolo[2,3-C]Pyridine, 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-value boronic ester derivative, a crucial building block in modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, specifically Suzuki-Miyaura couplings, which are fundamental for constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides through structure-activity relationship (SAR) studies.
• Material Science: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as those for OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Employed as a versatile handle for bioconjugation and the development of molecular probes and labeled compounds.
• Academic & Contract Research: A vital reagent for methodology development and complex molecule synthesis in academic and contract research organizations (CROs).

Basic Information

Product Name	1H-Pyrrolo[2,3-C]Pyridine, 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	1352227-38-3
Molecular Formula	C13H17BN2O2
Molecular Weight	244.10 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-c]pyridine; 1H-Pyrrolo[2,3-c]pyridine-4-boronic acid pinacol ester; 4-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-c]pyridine; 4-Borono-1H-pyrrolo[2,3-c]pyridine pinacol ester; 1H-Pyrrolo[2,3-c]pyridin-4-ylboronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-7-azaindole; 7-Azaindole-4-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-C]Pyridine, 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and LC-MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.