Description

Cyclobutanemethanethiol CAS NO 1352077-18-9 is a specialized organosulfur compound featuring a cyclobutane ring, valued for its unique steric and electronic properties derived from the constrained four-membered ring system. This compound serves as a critical building block in advanced organic synthesis, particularly for introducing sulfur-containing functional groups into complex molecular architectures. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Utilized in the synthesis of novel drug candidates, especially those requiring thiol or sulfide moieties for bioactivity or as prodrug linkers.
• Agrochemical Synthesis: Acts as a key precursor for creating new pesticides and herbicides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-catalyzed reactions, leveraging the steric bulk of the cyclobutyl group.
• Material Science Research: Used in the development of organic electronic materials, polymers, and coatings where the thiol group enables surface functionalization or cross-linking.
• Flavor & Fragrance Chemistry: Serves as a potential intermediate for synthesizing sulfur-containing aroma compounds with unique olfactory characteristics.
• Chemical Biology Probes: Incorporated into molecular probes for studying protein interactions and enzyme mechanisms via thiol-specific conjugation.

Basic Information

Product Name	Cyclobutanemethanethiol
CAS No.	1352077-18-9
Molecular Formula	C5H10S
Molecular Weight	102.20 g/mol
Synonyms	Cyclobutylmethanethiol; (Cyclobutylmethyl)thiol; Cyclobutanemethanethiol; 4-Thiapentylcyclobutane; Cyclobutylmethyl mercaptan; Mercaptomethylcyclobutane; Cyclobutane methanethiol
EINECS	Contact for details

Quality Control

Our Cyclobutanemethanethiol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results for purity, identity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use and stored away from heat, sparks, and open flame. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.