Description

Piperazin-1-Yl(Thiophen-3-Yl)Acetic Acid Dihydrochloride is a high-purity, pharmaceutically relevant building block and intermediate, valued for its unique heterocyclic structure combining piperazine and thiophene moieties. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel small molecule drug candidates targeting a range of therapeutic areas. It is primarily sought by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its versatile chemical scaffold.
• Chemical Biology Probe Development: Serves as a precursor for creating molecular probes to study biological pathways and protein interactions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the custom synthesis of complex molecules for clients.
• Library Synthesis: Used to generate focused chemical libraries for high-throughput screening (HTS) in drug discovery.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	Piperazin-1-Yl(Thiophen-3-Yl)Acetic Acid Dihydrochloride
CAS No.	1351582-77-8
Molecular Formula	C10H15Cl2N2O2S
Molecular Weight	298.21 g/mol
Synonyms	2-(Piperazin-1-yl)-2-(thiophen-3-yl)acetic acid dihydrochloride; 2-(1-Piperazinyl)-2-(3-thienyl)acetic acid dihydrochloride; (Thiophen-3-yl)(piperazin-1-yl)acetic acid dihydrochloride; 3-Thiopheneacetic acid, α-(1-piperazinyl)-, dihydrochloride; 1351582-77-8; UNII-8G8W4J8V3S; 8G8W4J8V3S
EINECS	Contact for details

Quality Control

Our Piperazin-1-Yl(Thiophen-3-Yl)Acetic Acid Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.