Description

8-Chloro-2-Phenyl-3-(1-(9-(Tetrahydro-2H-Pyran-2-Yl)-9H-Purin-6-Ylamino)Ethyl)Isoquinolin-1(2H)-One is a high-purity, advanced pharmaceutical intermediate designed for research and development. This compound is critical for medicinal chemists working on novel therapeutic agents, particularly in oncology and antiviral fields. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers requiring precise molecular building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel small-molecule drug candidates targeting specific biological pathways.
• Kinase Inhibitor Research: Used in the development and optimization of purine-based kinase inhibitors for cancer therapy.
• Medicinal Chemistry R&D: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead compound optimization.
• Process Chemistry: Employed in route scouting and scale-up studies for the production of active pharmaceutical ingredients (APIs).
• Biochemical Tool Compound: Used in vitro to study enzyme function and cellular signaling mechanisms in academic and industrial research settings.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial compounds for client-specific research programs.

Basic Information

Product Name	8-Chloro-2-Phenyl-3-(1-(9-(Tetrahydro-2H-Pyran-2-Yl)-9H-Purin-6-Ylamino)Ethyl)Isoquinolin-1(2H)-One
CAS No.	1350643-73-0
Molecular Formula	C27H23ClN6O2
Molecular Weight	498.96 g/mol
Synonyms	8-Chloro-2-phenyl-3-[1-[(9-tetrahydro-2H-pyran-2-yl-9H-purin-6-yl)amino]ethyl]isoquinolin-1(2H)-one; 8-Chloro-2-phenyl-3-(1-((9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-yl)amino)ethyl)isoquinolin-1(2H)-one; 1350643-73-0; THP-protected purine-isoquinolone conjugate; 6-((1-(8-Chloro-1-oxo-2-phenyl-1,2-dihydroisoquinolin-3-yl)ethyl)amino)-9-(tetrahydro-2H-pyran-2-yl)-9H-purine
EINECS	Contact for details

Quality Control

Our 8-Chloro-2-Phenyl-3-(1-(9-(Tetrahydro-2H-Pyran-2-Yl)-9H-Purin-6-Ylamino)Ethyl)Isoquinolin-1(2H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.