Description

5,6,7,8-Tetrahydro-1H-Benzo[B]Cyclopenta[D]Thiophen-3(2H)-One is a high-purity, advanced pharmaceutical intermediate with a complex fused-ring structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and proprietary drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex heterocyclic compounds and exploring new reaction pathways.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new-generation pesticides and herbicides with specific activity profiles.
• Material Science: Investigated as a monomer or precursor for specialty polymers and organic electronic materials due to its fused-ring, electron-rich structure.
• Chemical Reference Standard: Supplied as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical analysis.

Basic Information

Product Name	5,6,7,8-Tetrahydro-1H-Benzo[B]Cyclopenta[D]Thiophen-3(2H)-One
CAS No.	1346672-54-5
Molecular Formula	C11H12OS
Molecular Weight	192.28 g/mol
Synonyms	2,3,5,6,7,8-Hexahydrobenzo[b]thiophen-4(1H)-one; 5,6,7,8-Tetrahydro-4H-cyclopenta[b]thiophen-4-one; 4H-Cyclopenta[b]thiophen-4-one, 5,6,7,8-tetrahydro-; Tetrahydrobenzo[b]cyclopenta[d]thiophen-3(2H)-one; 1H-Benzo[b]cyclopenta[d]thiophen-3(2H)-one, 5,6,7,8-tetrahydro-; Advanced Pharmaceutical Intermediate 1346672-54-5
EINECS	Contact for details

Quality Control

Our 5,6,7,8-Tetrahydro-1H-Benzo[B]Cyclopenta[D]Thiophen-3(2H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.