Description

(αr)-n-(Methyl-D3)-α-Methyl-n-2-Propyn-1-Yl-Benzeneethanamine n-Oxide CAS NO 1346616-99-6 is a high-purity, deuterated chemical compound featuring a propynyl-substituted benzeneethanamine N-oxide core structure. This compound is of significant value in advanced research and development, particularly for its utility as a stable isotope-labeled internal standard or a sophisticated synthetic intermediate. It is primarily sought by professionals in pharmaceutical R&D, analytical chemistry, and specialized organic synthesis. The product is engineered to meet the stringent demands of modern chemical and life science applications.

Application

• As a deuterium-labeled internal standard for the precise quantification of related amine or N-oxide compounds in complex matrices using LC-MS or GC-MS.
• As a key advanced synthetic intermediate in the research and development of novel pharmaceutical candidates, particularly those targeting neurological pathways.
• For use in metabolic and pharmacokinetic (PK/ADME) studies to trace and understand the biological fate of drug molecules.
• In method development and validation within analytical laboratories to ensure accuracy, precision, and regulatory compliance.
• As a building block in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• For academic and institutional research exploring the chemistry and biological activity of functionalized amine N-oxides.

Basic Information

Product Name	(αr)-n-(Methyl-D3)-α-Methyl-n-2-Propyn-1-Yl-Benzeneethanamine n-Oxide
CAS No.	1346616-99-6
Molecular Formula	C13H14D3NO2
Molecular Weight	218.30 g/mol
Synonyms	N-Methyl-d3-α-methyl-N-(prop-2-yn-1-yl)phenethylamine N-oxide; (R)-N-(Methyl-d3)-α-methyl-N-(prop-2-yn-1-yl)benzenethanamine N-oxide; Deuterated N-Methylpropargylamine N-Oxide Derivative; Ar-N-(Methyl-d3)-α-Methyl-N-2-propynyl-Benzeneethanamine N-Oxide; 1-Phenyl-N-(prop-2-yn-1-yl)propan-2-amine N-oxide-d3; (R)-N-Methyl-d3-α-methyl-N-propargylphenethylamine N-oxide; Labeled Phenethylamine N-Oxide Derivative
EINECS	Contact for details

Quality Control

Our (αr)-n-(Methyl-D3)-α-Methyl-n-2-Propyn-1-Yl-Benzeneethanamine n-Oxide is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and MS, to confirm identity, chemical purity, and isotopic enrichment. Certificates of Analysis (COA) detailing all relevant specifications are provided to ensure full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep the container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 99.0 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.