Description

(R)-1-Aminoindane-D3 Hydrochloride is a chiral, deuterium-labeled building block and reference standard of significant value in advanced research and development. Its core value lies in providing a stable, isotopically labeled analog for metabolic, pharmacokinetic, and mechanistic studies, enhancing data accuracy and reliability. This high-purity compound is essential for pharmaceutical scientists, analytical chemists, and researchers in drug discovery, forensic analysis, and environmental testing who require definitive internal standards for mass spectrometry.

Application

• Internal Standard for LC-MS/MS: Serves as a critical, non-interfering reference compound for the precise quantification of aminoindane analogs and related pharmaceuticals in complex biological matrices.
• Metabolic Pathway Tracing: Utilized in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of drug molecules and identify metabolites due to its deuterium labeling.
• Pharmaceutical Reference Standard: Employed for method development, validation, and quality control in analytical laboratories to ensure accuracy and compliance with regulatory guidelines.
• Chiral Building Block: Used in the synthesis of more complex, isotopically labeled chiral molecules for research into neurological targets and receptor binding studies.
• Forensic and Clinical Toxicology: Acts as a definitive standard for the accurate identification and measurement of specific substances in forensic analysis and clinical toxicology reports.

Basic Information

Item	Detail
Product Name	(R)-1-Aminoindane-D3 Hydrochloride
CAS No.	1346616-96-3
Molecular Formula	C9H8D3ClN
Molecular Weight	170.67 g/mol
Synonyms	(R)-1-Aminoindan-1,2,2-d3 Hydrochloride; (1R)-2,3-Dihydro-1H-inden-1-amine-1,2,2-d3 Hydrochloride; (R)-1-Aminoindane-d3 HCl; (R)-1-Aminoindane (1,2,2-d3) Hydrochloride; Deuterated (R)-1-Aminoindane Hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-Aminoindane-D3 Hydrochloride is manufactured under strict quality systems to ensure high chemical and isotopic purity, critical for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing assay, chiral purity, isotopic enrichment (D%), and impurity profiles as determined by HPLC, NMR, and mass spectrometry. We adhere to cGMP principles for reference standard materials, ensuring traceability and reliability for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Isotopic Purity (D%)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.