Description

(E)-8-Hydroxy-n-[[4-Hydroxy-3-(Trideuteriomethoxy)Phenyl]Methyl]-8-Methylnon-6-Enamide is a deuterated bioactive compound of significant interest in advanced pharmaceutical research and development. Its core value lies in its utility as a stable isotope-labeled analog, enabling precise metabolic and pharmacokinetic studies. This high-purity chemical is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly for metabolic and neurological targets.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for analytical method development and validation in drug discovery pipelines.
• Metabolic Pathway Tracer: Used in mass spectrometry-based studies to track drug metabolism and distribution due to its deuterium-labeled methoxy group.
• Biochemical Research: Acts as a key intermediate or tool compound for investigating enzyme inhibition and receptor binding activities.
• Preclinical Development: Employed in in vitro and in vivo studies to establish pharmacokinetic (PK) and pharmacodynamic (PD) profiles of lead candidates.
• Active Pharmaceutical Ingredient (API) Synthesis: Utilized as a building block in the synthesis of deuterated drug candidates to enhance metabolic stability.

Basic Information

Product Name	(E)-8-Hydroxy-n-[[4-Hydroxy-3-(Trideuteriomethoxy)Phenyl]Methyl]-8-Methylnon-6-Enamide
CAS No.	1346606-77-6
Molecular Formula	C18H25D3NO4
Molecular Weight	337.44 g/mol
Synonyms	(E)-8-Hydroxy-N-[(4-hydroxy-3-(trideuteriomethoxy)phenyl)methyl]-8-methylnon-6-enamide; 8-Hydroxy-N-[[4-hydroxy-3-(trideuteriomethoxy)phenyl]methyl]-8-methyl-(E)-6-nonenamide; Deuterated Capsaicin Analog; CD3O-Capsaicin Derivative; (E)-8-Methyl-N-[(4-hydroxy-3-(methoxy-d3)phenyl)methyl]-6-nonenamide-8-ol; Nonivamide-d3 Derivative; Vanillyl-d3 Nonenamide
EINECS	Contact for details

Quality Control

Our (E)-8-Hydroxy-n-[[4-Hydroxy-3-(Trideuteriomethoxy)Phenyl]Methyl]-8-Methylnon-6-Enamide is manufactured under strict quality control protocols to ensure high chemical and isotopic purity, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results from advanced analytical techniques including NMR, HPLC, and MS. We adhere to cGMP principles where applicable to support regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure (¹H, ¹³C)
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98.0 atom % D (at CD3 position)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.