Description

2-(1-Hydroxyethyl) Promazine-D4 Sulfoxide is a high-purity, deuterium-labeled internal standard critical for modern analytical chemistry. This compound is specifically designed to ensure the accuracy and reliability of quantitative analysis in complex matrices. It is an essential tool for researchers and quality control laboratories in the pharmaceutical and forensic toxicology sectors who require precise measurement of promazine and related metabolites.

Application

• Primary use as an internal standard for the quantitative analysis of Promazine and its metabolites via LC-MS/MS and GC-MS.
• Method development and validation in pharmacokinetic and bioequivalence studies.
• High-accuracy quantification in forensic toxicology and therapeutic drug monitoring (TDM).
• Metabolite profiling and identification in drug metabolism and disposition (DMPK) research.
• Calibration standard for ensuring regulatory compliance in pharmaceutical quality control (QC) laboratories.
• Use in research investigating the environmental fate and analysis of phenothiazine derivatives.

Basic Information

Product Name	2-(1-Hydroxyethyl) Promazine-D4 Sulfoxide
CAS No.	1346605-30-8
Molecular Formula	C19H19D4N2OS
Molecular Weight	331.48 g/mol (for deuterated form)
Synonyms	Promazine-D4 Sulfoxide Hydroxyethyl Metabolite; 2-(1-Hydroxyethyl)promazine sulfoxide-d4; Deuterated Promazine Sulfoxide Metabolite; 10-[3-(Dimethylamino)propyl]-2-(1-hydroxyethyl)phenothiazine 5-oxide-d4; Promazine D4 ES; Promazine metabolite D4 internal standard
EINECS	Contact for details

Quality Control

Every batch of 2-(1-Hydroxyethyl) Promazine-D4 Sulfoxide is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity, verified by advanced spectroscopic and chromatographic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and solvent content is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. Due to its hygroscopic nature, the material should be handled in a dry environment and the container kept sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.