Description

n-(1,1-Dimethylethyl)-Benzenemethanamine-D9 Hydrobromide is a high-purity, deuterium-labeled organic salt used as a critical internal standard and reference material in analytical chemistry. Its primary value lies in enabling precise quantitative analysis and metabolic studies through mass spectrometry, ensuring data accuracy and reliability. This compound is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and forensic science industries who require stable isotope-labeled analogs for advanced analytical methods.

Application

• Internal Standard for LC-MS/MS: Used for the accurate quantification of its non-deuterated counterpart or related compounds in complex biological matrices like plasma, urine, and tissue homogenates.
• Metabolic Pathway Tracing: Employed in pharmacokinetic (PK) and absorption, distribution, metabolism, and excretion (ADME) studies to track drug metabolism and identify metabolites.
• Pharmaceutical Impurity Profiling: Serves as a reference standard in the development and validation of methods to detect and quantify process-related impurities and degradation products.
• Forensic and Clinical Toxicology: Facilitates the precise measurement of specific analytes in forensic analysis and therapeutic drug monitoring (TDM) programs.
• Isotope Dilution Mass Spectrometry (IDMS): A key component in this gold-standard technique for achieving high-accuracy and high-precision measurements in research and regulatory testing.
• Chemical Synthesis Research: Acts as a deuterated building block or intermediate in the synthesis of more complex labeled compounds for research purposes.

Basic Information

Product Name	n-(1,1-Dimethylethyl)-Benzenemethanamine-D9 Hydrobromide
CAS No.	1346605-21-7
Molecular Formula	C11H9D9BrN
Molecular Weight	244.21 g/mol
Synonyms	N-tert-Butylbenzylamine-d9 Hydrobromide; tert-Butylbenzylamine-d9 HBr; Benzenemethanamine, N-(1,1-dimethylethyl)-, hydrobromide, d9; Benzyl-tert-butylamine-d9 Hydrobromide; (tert-Butylamino-d9)methylbenzene Hydrobromide; N-(tert-Butyl)-benzylamine-d9 Hydrobromide; Deuterated N-tert-Butylbenzylamine HBr; N-t-Butylbenzylamine-d9 Hydrobromide Salt
EINECS	Contact for details

Quality Control

Every batch of n-(1,1-Dimethylethyl)-Benzenemethanamine-D9 Hydrobromide is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity, verified by advanced analytical techniques including NMR (¹H, ¹³C), mass spectrometry, and HPLC. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and all specification results is provided with each shipment to ensure traceability and compliance with your research or quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere in a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.