Description

Ethyl Nicotinate-1,2',3',4',5',6'-13C6 Hydrochloride Salt is a stable isotope-labeled derivative of ethyl nicotinate, where all six carbon atoms in the pyridine ring are replaced with the 13C isotope. This high-purity labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring unparalleled accuracy and reliability in analytical measurements. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, agrochemical, and metabolomics fields for method development, validation, and precise quantification of nicotinate esters and related metabolites.

Application

• Internal Standard for LC-MS/MS and GC-MS: Critical for accurate quantification of ethyl nicotinate and its metabolites in complex biological matrices like plasma, urine, and tissue homogenates.
• Pharmaceutical Research & Development: Used in pharmacokinetic (PK) and pharmacodynamic (PD) studies, drug metabolism and disposition (DMPK) assays, and bioanalytical method validation.
• Metabolomics and Biomarker Discovery: Enables precise tracking and measurement of nicotinic acid pathways in metabolic flux analysis and clinical research.
• Agrochemical Analysis: Serves as a reference standard for the detection and quantification of pesticide metabolites or related compounds in environmental and food safety testing.
• Forensic Toxicology: Supports the accurate analysis of relevant compounds in forensic investigations requiring high evidentiary standards.
• Quality Control & Regulatory Compliance: Essential for laboratories requiring GLP/GMP compliance, providing traceable and definitive standards for assay calibration.

Basic Information

Product Name	Ethyl Nicotinate-1,2',3',4',5',6'-13C6 Hydrochloride Salt
CAS No.	1346604-87-2
Molecular Formula	C813C6H12ClNO2
Molecular Weight	Contact for details
Synonyms	Ethyl Nicotinate-13C6 Hydrochloride; Ethyl 3-Pyridinecarboxylate-13C6 Hydrochloride; Nicotinic Acid Ethyl Ester-13C6 HCl; 3-CarbethoxyPyridine-13C6 Hydrochloride; [13C6]-Ethyl Nicotinate HCl; Ethyl Niacinate-13C6 Hydrochloride; Isotopically Labeled Ethyl Nicotinate HCl; 13C6-Ethyl Nicotinate Hydrochloride Salt
EINECS	Contact for details

Quality Control

Every batch of Ethyl Nicotinate-13C6 Hydrochloride Salt is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity, with comprehensive testing including NMR, HPLC, and mass spectrometry to confirm structure, isotopic enrichment, and potency. Certificates of Analysis (COA) are provided with each shipment, detailing batch-specific results. Our production adheres to standards suitable for research and analytical applications under ISO-guided practices.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Enrichment	≥99 atom % 13C
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.