Description

2,4-Dichloro-5-Nitrophenyl Isopropyl-D7 Ether is a deuterated aromatic ether compound featuring selective isotopic labeling (D7) at the isopropyl group, designed for high-precision analytical applications. Its structural specificity and isotopic enrichment make it an essential internal standard in quantitative mass spectrometry workflows—ensuring exceptional accuracy, reproducibility, and signal discrimination in complex matrices. This compound is critically utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and regulatory testing facilities engaged in metabolite quantification, stability-indicating assays, and bioanalytical method validation.

Application

• Internal standard for LC-MS/MS quantification of 2,4-dichloro-5-nitrophenyl ether analogs in biological fluids (plasma, urine)
• Reference material for method development and validation in FDA/EMA-regulated bioequivalence and pharmacokinetic studies
• Isotopic tracer in mechanistic metabolism studies of nitroaromatic pesticides and pharmaceutical intermediates
• Calibration standard for residue analysis in environmental monitoring (soil, water) and food safety testing
• Stable isotope-labeled control in forensic toxicology screening for chlorinated nitrophenol derivatives
• Quality assurance benchmark in GMP-compliant reference standard manufacturing

Basic Information

Product Name	2,4-Dichloro-5-Nitrophenyl Isopropyl-D7 Ether
CAS No.	1346604-56-5
Molecular Formula	C9D7Cl2NO3
Molecular Weight	271.08 g/mol
Synonyms	2,4-Dichloro-5-nitrophenyl-1,1,1,2,2,2,2-d7-isopropyl ether; 2,4-Dichloro-5-nitrophenyl (1,1,1,2,2,2,2-d7)isopropyl ether; D7-2,4-DCNP-IPE; 2,4-Dichloro-5-nitrophenyl isopropyl-d7 ether; 5-Nitro-2,4-dichlorophenyl isopropyl-d7 ether; Isopropyl-d7 ether of 2,4-dichloro-5-nitrophenol; NSC 1346604-56-5; [D7]-2,4-Dichloro-5-nitrophenyl isopropyl ether
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. All batches are verified for isotopic purity (>99.0 atom% D), chemical identity (NMR, IR, MS), assay (HPLC), and impurity profile (residual solvents, heavy metals, related substances) per ICH Q2(R2) guidelines. Manufactured under ISO 9001-certified quality management systems with full traceability from synthesis to packaging.

Storage

Preserve in a tightly closed container, protected from light. Store at 2–8 °C under inert atmosphere (argon or nitrogen) to prevent degradation. Keep away from strong oxidizing agents and avoid repeated exposure to ambient humidity.

Specification

Item	Specification
Appearance	Pale yellow to off-white crystalline solid
Isotopic Purity (D7)	≥99.0 atom% D
Chemical Purity (HPLC)	≥98.5%
Identity (MS)	Conforms to expected m/z (M+): 271.08 ± 0.02
Identity (IR)	Conforms to reference spectrum (characteristic NO2, C–O, C–Cl absorptions)
Residual Solvents (GC)	Meets ICH Q3C Class 3 limits
Water Content (KF)	≤0.5%
Heavy Metals (ICP-MS)	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.