Description

3-Amino-4-(Propylamino)-3-Cyclobutene-1,2-Dione-D7 is a deuterated derivative of a cyclobutenedione derivative, serving as a crucial stable isotope-labeled building block for advanced research and development. This compound is specifically designed for applications requiring high isotopic purity and structural integrity, enabling precise tracking and analysis in complex chemical and biological systems. It is primarily utilized by pharmaceutical researchers, agrochemical developers, and analytical chemists working in drug metabolism studies (DMPK), proteomics, and the synthesis of novel labeled compounds.

Application

• Deuterated Internal Standards for quantitative mass spectrometry (LC-MS/MS, GC-MS) in bioanalytical and environmental analysis.
• Pharmaceutical Research as a labeled intermediate in the synthesis of deuterated drug candidates for improved metabolic stability and pharmacokinetic studies.
• Metabolite Identification & Tracing in drug metabolism and disposition (DMPK) research to elucidate metabolic pathways.
• Chemical Biology Probes for studying reaction mechanisms and protein interactions using isotope labeling techniques.
• Agrochemical Development for creating isotopically labeled pesticides or herbicides to study environmental fate and degradation.
• NMR Spectroscopy as a tool for structural elucidation and complex mixture analysis due to its distinct deuterium signature.

Basic Information

Product Name	3-Amino-4-(Propylamino)-3-Cyclobutene-1,2-Dione-D7
CAS No.	1346604-28-1
Molecular Formula	C7H2D7N2O2
Molecular Weight	158.21 g/mol (approx.)
Synonyms	3-Amino-4-(propylamino)-3-cyclobutene-1,2-dione (heptadeutero); 3-Amino-4-propylaminocyclobut-3-ene-1,2-dione-D7; 1,2-Cyclobutenedione, 3-amino-4-(propylamino)-, D7-labeled; Deuterated Squaric Acid Diamide Derivative; 3-Amino-4-(propylamino)cyclobut-3-ene-1,2-dione (D7); [D7]-3-Amino-4-(propylamino)-3-cyclobutene-1,2-dione
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality systems to ensure high isotopic purity and chemical integrity. Each batch is characterized by advanced analytical techniques including NMR (¹H, ²H) and mass spectrometry. A comprehensive Certificate of Analysis (COA) is provided, detailing isotopic enrichment (D-content), chemical purity, and identity confirmation. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Purity (²H NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.