Description

(4H-1,2,4-Triazol-3-Yl)Amine-13C2,15N2 is a high-purity, isotopically labeled derivative of the 1,2,4-triazole scaffold, specifically enriched with carbon-13 and nitrogen-15 at key positions. This compound is critical for advanced analytical research, providing a stable, non-radioactive tracer for precise metabolic and pharmacokinetic studies. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical developers, and academic institutions engaged in sophisticated mass spectrometry and NMR-based analysis.

Application

• Internal Standard for LC-MS/MS: Serves as a quantitative reference standard in bioanalytical method development for drug metabolism and pharmacokinetics (DMPK) studies.
• Metabolic Pathway Tracing: Used as a stable isotope-labeled probe to elucidate metabolic pathways and identify metabolites of triazole-based active pharmaceutical ingredients (APIs).
• Proteomics & Biomarker Research: Employed in chemical proteomics for target identification and in the development of assays for biomarker discovery.
• Agrochemical Environmental Fate Studies: Applied in research to track the environmental degradation and uptake of triazole-class fungicides and herbicides.
• NMR Spectroscopy: Provides distinct spectral signatures for structural elucidation and dynamic studies of molecules incorporating the triazole moiety.
• Synthesis of Labeled Compounds: Acts as a key building block for the synthesis of more complex isotopically labeled molecules for research and diagnostic purposes.

Basic Information

Product Name	(4H-1,2,4-Triazol-3-Yl)Amine-13C2,15N2
CAS No.	1346603-92-6
Molecular Formula	13C2H4N3
Molecular Weight	86.06 g/mol (for labeled form)
Synonyms	3-Amino-1,2,4-triazole-13C2,15N2; 1H-1,2,4-Triazol-3-amine-13C2,15N2; Amitrole-13C2,15N2; 3-AT-13C2,15N2; ATA-13C2,15N2; 3-Amino-s-triazole-13C2,15N2; Isotopically Labeled Amitrole
EINECS	Contact for details

Quality Control

Every batch of (4H-1,2,4-Triazol-3-Yl)Amine-13C2,15N2 is manufactured and analyzed under strict quality systems. We guarantee high chemical and isotopic purity, with comprehensive testing including NMR and mass spectrometry to confirm isotopic enrichment and positional labeling. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, isotopic abundance, and analytical results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (MS)	≥98 atom % 13C, ≥98 atom % 15N
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.