Description

Rac Secoisolariciresinol-D6 is a deuterium-labeled isotopologue of the natural lignan secoisolariciresinol, specifically designed for use as an internal standard in quantitative analytical chemistry. This high-purity compound is essential for ensuring accuracy and reliability in mass spectrometry-based assays, particularly in pharmacokinetic and metabolic studies. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, nutraceutical, and life science sectors who require precise measurement of secoisolariciresinol and its metabolites.

Application

• Internal Standard for LC-MS/MS: Primary application for the accurate quantification of secoisolariciresinol in complex biological matrices like plasma, serum, and urine.
• Pharmaceutical R&D: Used in drug metabolism and pharmacokinetics (DMPK) studies to track the absorption, distribution, metabolism, and excretion of lignan-based therapeutics.
• Nutraceutical & Food Analysis: Enables precise measurement of secoisolariciresinol content in functional foods, dietary supplements, and plant extracts for quality assurance and labeling compliance.
• Biomarker Research: Facilitates clinical studies investigating lignans as biomarkers for dietary intake or their role in disease prevention.
• Method Development & Validation: Serves as a critical component in developing and validating robust analytical methods in compliance with ICH, FDA, and other regulatory guidelines.

Basic Information

Product Name	Rac Secoisolariciresinol-D6
CAS No.	1346603-90-4
Molecular Formula	C20H20D6O6
Molecular Weight	368.45 g/mol
Synonyms	(±)-Secoisolariciresinol-D6; DL-Secoisolariciresinol-D6; Rac-2,3-Bis[(4-hydroxy-3-methoxyphenyl)methyl]butane-1,4-diol-D6; 2,3-Bis(4-hydroxy-3-methoxybenzyl)butane-1,4-diol-D6; SDG-D6; Secoisolariciresinol Diglucoside Aglycone-D6; LGM2695-D6; HMRlignan-D6
EINECS	Contact for details

Quality Control

Every batch of Rac Secoisolariciresinol-D6 is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure the highest standards of isotopic purity and chemical identity. Our quality commitment includes comprehensive characterization by NMR, HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming specifications for isotopic enrichment, chemical purity, and absence of interfering impurities.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D6)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.