Description

3-Chloro Fenofibric Acid-D6 is a stable isotope-labeled analog of a key fenofibric acid metabolite, specifically designed for use as an internal standard in quantitative analytical methods. This high-purity compound is essential for ensuring accuracy and precision in mass spectrometry-based analyses, particularly in pharmacokinetic and metabolic studies. It is primarily utilized by pharmaceutical research and development laboratories, contract research organizations (CROs), and analytical testing facilities focused on drug metabolism and bioanalytical method development.

Application

• Internal Standard for LC-MS/MS: Critical for the accurate quantification of 3-chloro fenofibric acid and related compounds in complex biological matrices such as plasma, serum, and urine.
• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Enables precise tracking of drug metabolite formation, distribution, and elimination in preclinical and clinical research.
• Bioanalytical Method Development and Validation: Serves as a reliable reference standard to establish selectivity, sensitivity, linearity, and reproducibility of analytical assays.
• Clinical Trial Support: Used in the bioanalysis phase of clinical trials to monitor drug and metabolite levels in patient samples, ensuring data integrity for regulatory submissions.
• Forensic and Anti-Doping Analysis: Can be employed in specialized testing protocols for the definitive identification and quantification of specific substances.
• Quality Control in Pharmaceutical Manufacturing: Supports impurity profiling and stability testing of active pharmaceutical ingredients (APIs) and finished drug products.

Basic Information

Item	Details
Product Name	3-Chloro Fenofibric Acid-D6
CAS No.	1346603-07-3
Molecular Formula	C17H11D6ClO4
Molecular Weight	334.80 g/mol (for deuterated form)
Synonyms	3-Chloro Fenofibric Acid-d6; 2-[4-(3-Chlorobenzoyl)phenoxy]-2-methylpropanoic-d6 Acid; Deuterated 3-Chloro Fenofibric Acid; 3-Chloro-2-[4-(3-chlorobenzoyl)phenoxy]-2-methylpropanoic-d6 Acid; Isotope Labeled 3-Chloro Fenofibric Acid; 3-Chloro Fenofibric Acid (D6); 3-Chloro Fenofibric Acid Internal Standard; 3-Chloro-Isotopically Labeled Fenofibric Acid
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro Fenofibric Acid-D6 is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure exceptional isotopic purity and chemical identity. Our quality commitment includes comprehensive characterization by NMR, HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific data for isotopic enrichment, chemical purity, and other critical parameters to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D6)	≥ 98.0 atom % D
Chemical Purity (by HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.