Description

Dihydrocuscohygrine-D6 is a deuterium-labeled isotopologue of the natural alkaloid dihydrocuscohygrine, specifically designed for use as an internal standard in advanced analytical chemistry. This compound is critical for ensuring the accuracy and reliability of quantitative analyses, particularly in mass spectrometry, by correcting for variations in sample preparation and instrument response. It is an essential tool for researchers and quality control laboratories in the pharmaceutical, forensic, and phytochemical industries who require precise measurement of coca alkaloids and related tropane derivatives.

Application

• Internal Standard for LC-MS/MS and GC-MS quantification of cuscohygrine, hygrine, and related alkaloids.
• Metabolite tracking and pharmacokinetic studies in pharmaceutical research involving tropane alkaloids.
• Forensic analysis and doping control for the precise identification and quantification of banned substances.
• Biochemical research investigating the biosynthetic pathways of plant-derived alkaloids.
• Quality control and method validation in herbal medicine and natural product standardization.
• Environmental and agricultural testing for alkaloid residue analysis.

Basic Information

Product Name	Dihydrocuscohygrine-D6
CAS No.	1346602-92-3
Molecular Formula	C13H20D6N2O
Molecular Weight	236.39 g/mol
Synonyms	1-Methyl-2-[5-(methyl-d3)-1-pyrrolidinyl-d3]-5-pyrrolidinone; Dihydrocuscohygrine-d6; (2R,2'R)-2-(1-Methyl-5-oxo-3-pyrrolidinyl)-1-methyl-2-pyrrolidineacetic Acid-d6; Deuterated Dihydrocuscohygrine; Cuscohygrine-d6 Internal Standard
EINECS	Contact for details

Quality Control

Our Dihydrocuscohygrine-D6 is produced under strict quality management protocols to ensure the high chemical purity and isotopic enrichment required for analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results for identity, purity (by HPLC), isotopic purity (by MS), and residual solvents. We adhere to relevant industry standards for reference materials, and custom purity grades or certified reference material (CRM) status can be discussed to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at 2-8°C. Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.