Description

n-(2-Aminoethyl)-4-(1,1-Dimethylethyl)-2,6-Dimethylbenzeneacetamide-D4 is a deuterated analog of a key benzamide derivative, serving as a critical stable isotope-labeled intermediate for advanced research and development. Its primary value lies in enabling precise analytical quantification and metabolic pathway tracing in pharmacokinetic and environmental fate studies. This high-purity compound is essential for pharmaceutical researchers, analytical chemists, and contract research organizations (CROs) developing and validating sensitive LC-MS/MS methods.

Application

• Internal Standard for Mass Spectrometry: Used as a deuterium-labeled internal standard (IS) for the accurate quantification of its non-deuterated counterpart in bioanalytical methods, minimizing matrix effects and improving data reliability.
• Pharmaceutical Metabolism Studies: Facilitates Absorption, Distribution, Metabolism, and Excretion (ADME) studies and pharmacokinetic (PK) profiling in drug development pipelines.
• Environmental Analysis: Enables the precise tracking and analysis of chemical residues or transformation products in complex environmental samples.
• Clinical Research: Supports therapeutic drug monitoring (TDM) and clinical trial sample analysis where high specificity and accuracy are mandated.
• Chemical Synthesis Research: Acts as a specialized building block or tracer in synthetic chemistry for mechanistic studies.
• Regulatory Compliance Testing: Critical for developing and validating methods that comply with Good Laboratory Practice (GLP) and regulatory guidelines (e.g., FDA, EMA).

Basic Information

Product Name	n-(2-Aminoethyl)-4-(1,1-Dimethylethyl)-2,6-Dimethylbenzeneacetamide-D4
CAS No.	1346602-56-9
Molecular Formula	C16H22D4N2O
Molecular Weight	262.40 g/mol (approx.)
Synonyms	4-tert-Butyl-2,6-dimethyl-N-(2-aminoethyl)benzamide-d4; 2,6-Dimethyl-4-tert-butyl-N-(2-aminoethyl)benzamide-d4; Deuterated Benzamide Intermediate; [D4]-Labeled Benzamide Derivative; Stable Isotope-Labeled Internal Standard; n-(2-Aminoethyl)-4-tert-butyl-2,6-dimethylbenzamide-d4; 4-(tert-Butyl)-2,6-dimethyl-N-(2-aminoethyl)benzamide-d4
EINECS	Contact for details

Quality Control

Our deuterated compounds are manufactured under strict quality systems to ensure high isotopic purity and chemical integrity. Each batch is characterized by advanced analytical techniques including NMR, HPLC, and high-resolution mass spectrometry. A comprehensive Certificate of Analysis (COA) is provided, detailing isotopic enrichment (typically >98 atom % D), chemical purity, and confirming identity. We support GLP-compliant research and can supply materials suitable for regulated studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.