Description

2-(Cyclopropylmethoxy-D4)-Acetic Acid is a deuterated derivative of a cyclopropylmethyl ether acetic acid compound, where four hydrogen atoms are replaced with the stable isotope deuterium. This deuteration is critical for enhancing metabolic stability and traceability in research, making it a valuable tool for pharmacokinetic and mechanistic studies. It is primarily utilized by pharmaceutical researchers and agrochemical developers as a stable isotope-labeled intermediate or reference standard.

Application

• Pharmaceutical Research: Used as a stable isotope-labeled intermediate in the synthesis of deuterated drug candidates for improved ADME (Absorption, Distribution, Metabolism, Excretion) studies.
• Metabolite Tracing: Serves as a crucial internal standard in LC-MS and GC-MS analytical methods for the accurate quantification of metabolites in biological matrices.
• Mechanistic Studies: Employed in chemical and biochemical research to investigate reaction pathways and mechanisms using isotope effects.
• Agrochemical Development: Acts as a labeled building block in the research and development of novel, traceable crop protection agents.
• Material Science: Potential use in the synthesis of specialized polymers or ligands where isotopic labeling is required for spectroscopic analysis.

Basic Information

Product Name	2-(Cyclopropylmethoxy-D4)-Acetic Acid
CAS No.	1346602-05-8
Molecular Formula	C6H6D4O3
Molecular Weight	130.17 g/mol (for deuterated form)
Synonyms	2-[(Cyclopropylmethyl-d4)oxy]acetic Acid; Acetic Acid, 2-[(Cyclopropylmethyl-d4)oxy]-; Deuterated Cyclopropylmethyloxyacetic Acid; (Cyclopropylmethoxy-d4)acetic Acid; [D4]-2-(Cyclopropylmethoxy)acetic Acid; 2-(Cyclopropylmethyloxy-d4)acetic Acid; CPMA-d4
EINECS	Contact for details

Quality Control

Every batch of 2-(Cyclopropylmethoxy-D4)-Acetic Acid is produced and analyzed under strict quality management protocols. We ensure high chemical purity and isotopic enrichment suitable for advanced research applications. Comprehensive Certificates of Analysis (COA) detailing purity (by HPLC/GC), isotopic purity (by NMR/MS), and other critical parameters are provided with each shipment to guarantee traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR/NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.