Description

2-[1-(Trideuteriomethyl)Piperidin-2-Yl]Ethanol is a deuterated piperidine derivative, a high-value specialty chemical designed for advanced research and development. This compound is critical for applications requiring isotopic labeling, offering enhanced metabolic stability and traceability in analytical studies. It is primarily utilized by pharmaceutical researchers, agrochemical developers, and analytical chemists working in drug discovery, metabolic pathway analysis, and the synthesis of labeled reference standards.

Application

• Pharmaceutical Research: Used as a deuterium-labeled building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs) for pharmacokinetic and metabolic stability studies.
• Metabolite Identification: Serves as a crucial internal standard or tracer in LC-MS and NMR-based assays for accurate metabolite profiling and quantification.
• Agrochemical Development: Employed in the research and synthesis of isotopically labeled pesticides and herbicides to study environmental fate and degradation pathways.
• Analytical Reference Standard: Provides a high-purity certified material for use as a calibration standard in quantitative mass spectrometry and other analytical techniques.
• Medicinal Chemistry: Acts as a key intermediate for structure-activity relationship (SAR) studies, enabling the exploration of deuterium isotope effects on drug potency and selectivity.
• Isotope Labeling Services: Supplied to CROs and CDMOs specializing in custom synthesis of deuterated compounds for client-specific research programs.

Basic Information

Product Name	2-[1-(Trideuteriomethyl)Piperidin-2-Yl]Ethanol
CAS No.	1346601-98-6
Molecular Formula	C9H16D3NO
Molecular Weight	160.26 g/mol (Calculated)
Synonyms	2-(1-(Trideuteriomethyl)-2-piperidinyl)ethanol; 2-(1-(Methyl-d3)-2-piperidinyl)ethanol; 2-(1-(CD3)-Piperidin-2-yl)ethanol; Deuterated 2-(1-Methylpiperidin-2-yl)ethanol; 2-(1-Methyl-2-piperidinyl)ethanol-d3; 2-Piperidineethanol, 1-methyl-, 1-methyl-d3-; (2-Piperidinyl)ethanol, 1-(trideuteriomethyl)-
EINECS	Contact for details

Quality Control

Our deuterated chemicals are produced under strict quality control protocols to ensure isotopic purity and chemical integrity. Each batch is characterized by advanced analytical techniques including NMR (for deuterium incorporation), GC-MS, and HPLC. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing assay purity, isotopic enrichment, and impurity profiles. We support compliance with cGMP and ISO 9001 standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to maintain stability and prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium NMR)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.