Description

6-(Trideuteriomethylsulfanyl)-7H-Purin-2-Amine is a deuterated purine derivative, a high-value building block for advanced research and development. Its core value lies in the incorporation of stable deuterium atoms, which are critical for modifying metabolic pathways and enhancing the analytical properties of molecules. This compound is essential for researchers and developers in the pharmaceutical and agrochemical industries, particularly for applications in drug discovery, metabolic studies, and the synthesis of labeled compounds for use as internal standards in mass spectrometry.

Application

• Pharmaceutical Research & Drug Discovery: Used as a deuterated intermediate in the synthesis of novel active pharmaceutical ingredients (APIs) to study isotope effects on metabolism, bioavailability, and toxicity.
• Metabolic Pathway Tracing: Serves as a stable isotope-labeled tracer in biochemical and pharmacological studies to investigate drug metabolism and enzymatic mechanisms.
• Mass Spectrometry Internal Standards: A key precursor for synthesizing high-purity, deuterium-labeled internal standards essential for accurate quantitative analysis (LC-MS/MS, GC-MS).
• Agrochemical Development: Employed in the research and synthesis of new, potentially more effective or selective agrochemicals with modified environmental persistence.
• Biochemical Probe Synthesis: Utilized to create labeled probes for studying purine-based biological processes and receptor interactions.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting cutting-edge research in medicinal chemistry and chemical biology.

Basic Information

Product Name	6-(Trideuteriomethylsulfanyl)-7H-Purin-2-Amine
CAS No.	1346601-96-4
Molecular Formula	C6H4D3N5S
Molecular Weight	186.22 g/mol
Synonyms	2-Amino-6-(trideuteriomethylthio)purine; 6-(Trideuteromethylthio)-7H-purin-2-amine; 2-Amino-6-((methyl-d3)thio)purine; Deuterated 6-Methylmercaptopurine derivative; 6-(Methyl-d3-sulfanyl)-7H-purin-2-amine; 6-(Trideuteromethylsulfanyl)purine-2-amine; 2-Aminopurine-6-(methyl-d3) sulfide
EINECS	Contact for details

Quality Control

Our 6-(Trideuteriomethylsulfanyl)-7H-Purin-2-Amine is manufactured under strict quality systems to ensure batch-to-batch consistency and high isotopic purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chemical purity (by HPLC), isotopic enrichment (by NMR/MS), and identity confirmation. We adhere to cGMP principles for advanced intermediates, ensuring traceability and reliability for critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D3, by MS)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.