Description

α-[2-(Dimethylamino-D6)Ethyl] Hydrocinnamic Acid Ethyl Ester is a deuterated derivative of a key intermediate used in the synthesis of complex organic molecules. This compound is of significant value for research and development in the pharmaceutical and agrochemical sectors, where deuterium labeling is employed to study metabolic pathways, improve pharmacokinetic profiles, and enhance the stability of active ingredients. It is primarily sought by medicinal chemists, process development scientists, and manufacturers of fine chemicals and active pharmaceutical ingredients (APIs) requiring isotopically labeled building blocks.

Application

• Pharmaceutical Research & Development: As a deuterated intermediate in the synthesis of novel drug candidates, particularly for metabolic studies and the development of deuterated drugs with improved efficacy and safety profiles.
• Agrochemical Synthesis: Used in the creation of isotopically labeled pesticides or herbicides for environmental fate studies and metabolic pathway analysis.
• Metabolite Identification & Tracing: Serves as a crucial tool in ADME (Absorption, Distribution, Metabolism, and Excretion) studies to track and identify metabolites using mass spectrometry.
• Process Chemistry & Scale-up: Employed as a specialized building block in process optimization and the commercial-scale production of deuterium-labeled fine chemicals.
• Analytical Reference Standard: Used as a high-purity internal standard in quantitative LC-MS and GC-MS analyses for accurate measurement of non-deuterated analogs in complex matrices.
• Chemical Biology Probes: Facilitates the development of molecular probes for investigating biological mechanisms and protein interactions.

Basic Information

Item	Detail
Product Name	α-[2-(Dimethylamino-D6)Ethyl] Hydrocinnamic Acid Ethyl Ester
CAS No.	1346601-78-2
Molecular Formula	C15H19D6NO2
Molecular Weight	253.40 g/mol
Synonyms	Ethyl 3-[2-(Dimethylamino-d6)ethyl]hydrocinnamate; 3-[2-(Dimethylamino-d6)ethyl]hydrocinnamic Acid Ethyl Ester; Ethyl 3-[2-(N,N-Dimethyl-d6-amino)ethyl]phenylpropionate; (3-(2-(Dimethylamino-d6)ethyl)phenyl)propanoic Acid Ethyl Ester; Deuterated Hydrocinnamic Acid Ethyl Ester Derivative; A-[2-(Dimethylamino-D6)Ethyl]Hydrocinnamic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our deuterated chemicals are produced under strict quality management systems. Each batch of α-[2-(Dimethylamino-D6)Ethyl] Hydrocinnamic Acid Ethyl Ester undergoes rigorous analytical testing, including NMR (¹H, ¹³C, and deuterium), HPLC, and mass spectrometry, to confirm chemical identity, isotopic purity (D-enrichment), and chemical purity. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.