Description

Dimethyl(3,3-Difluoro-2-Oxoheptyl)Phosphonate-D7 is a deuterated organophosphorus compound, specifically a phosphonate ester, serving as a critical labeled intermediate in advanced synthetic chemistry. Its core value lies in enabling precise metabolic and pharmacokinetic studies by providing a stable, non-radioactive isotopic label. This high-purity compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of deuterated drug candidates, enhancing metabolic stability and enabling drug metabolism and pharmacokinetics (DMPK) studies.
• Agrochemical Research: Used in creating labeled analogs of pesticides and herbicides to study environmental fate, degradation pathways, and residue analysis.
• Metabolic Pathway Tracing: Employed in biomedical research as a tracer to elucidate biochemical pathways and mechanisms of action in biological systems.
• Analytical Standard: Serves as a certified reference material (CRM) or internal standard for quantitative mass spectrometry (LC-MS, GC-MS) in bioanalytical laboratories.
• Organic Synthesis: Functions as a specialized reagent in Horner-Wadsworth-Emmons (HWE) olefination reactions to introduce deuterated, fluorinated alkene segments.
• Isotope Labeling Services: A critical material for contract research organizations (CROs) and CDMOs offering custom deuterium labeling services.

Basic Information

Product Name	Dimethyl(3,3-Difluoro-2-Oxoheptyl)Phosphonate-D7
CAS No.	1346601-73-7
Molecular Formula	C9H8D7F2O4P
Molecular Weight	263.19 g/mol (approx.)
Synonyms	Dimethyl (3,3-Difluoro-2-oxoheptyl-d7)phosphonate; (3,3-Difluoro-2-oxoheptyl-d7)phosphonic Acid Dimethyl Ester; Deuterated Dimethyl (3,3-Difluoro-2-oxoheptyl)phosphonate; Heptanoyl-d7, 3,3-difluoro-, dimethyl phosphate; Phosphonic Acid, (3,3-Difluoro-2-oxoheptyl-d7)-, Dimethyl Ester
EINECS	Contact for details

Quality Control

Our Dimethyl(3,3-Difluoro-2-Oxoheptyl)Phosphonate-D7 is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity for research and cGMP applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as chemical purity (by HPLC), isotopic enrichment (D-content by 1H/2H NMR or MS), and identity confirmation. We adhere to rigorous analytical standards to guarantee batch-to-batch consistency and reliability for your critical synthetic and analytical workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0% (Area %)
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.