Description

5-[2-(1,1,1,2,3,3,3-Heptadeuteriopropan-2-Ylamino)-1-Hydroxyethyl]Benzene-1,3-Diol is a deuterated analog of a key pharmaceutical intermediate, offering enhanced metabolic stability and traceability for advanced research and development. This high-purity compound is critical for pharmacokinetic studies, metabolic pathway analysis, and the development of deuterated drug substances. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers of active pharmaceutical ingredients (APIs) focused on innovative therapeutic agents.

Application

• Deuterated Drug Development: As a stable isotope-labeled building block for creating new chemical entities with improved metabolic profiles.
• Pharmacokinetic & Metabolic Studies: Used as an internal standard in LC-MS and GC-MS for accurate quantification and metabolite identification in biological matrices.
• Mechanism of Action (MoA) Research: Enables tracing of biochemical pathways to elucidate drug mechanisms without interfering with biological activity.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method validation in pharmaceutical manufacturing.
• Isotope Labeling Services: A key material for custom synthesis and contract manufacturing of labeled compounds for clinical trials.

Basic Information

Item	Details
Product Name	5-[2-(1,1,1,2,3,3,3-Heptadeuteriopropan-2-Ylamino)-1-Hydroxyethyl]Benzene-1,3-Diol
CAS No.	1346601-49-7
Molecular Formula	C11H11D7NO3
Molecular Weight	Approx. 221.29 g/mol
Synonyms	5-[2-[(1,1,1,2,3,3,3-Heptadeuterio-2-propanyl)amino]-1-hydroxyethyl]-1,3-benzenediol; Deuterated Isoproterenol-d7; 3,4-Dihydroxy-α-[(1,1,1,2,3,3,3-heptadeuterio-2-propylamino)methyl]benzyl Alcohol-d7; d7-Isoproterenol; DL-Isoproterenol-d7; (±)-Isoproterenol-d7; 1-(3,4-Dihydroxyphenyl)-2-[(1,1,1,2,3,3,3-heptadeuterio-2-propyl)amino]ethanol-d0; Isotope-labeled adrenergic agonist intermediate
EINECS	Contact for details

Quality Control

Our deuterated compounds are manufactured under strict quality management systems. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry to confirm isotopic enrichment and chemical purity. A comprehensive Certificate of Analysis (COA) is provided, detailing assay, isotopic purity, and impurity profiles to support regulatory filings (e.g., FDA, EMA). We adhere to cGMP principles where applicable for pharmaceutical-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere (argon or nitrogen) to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.