Description

2,6-Difluorophenylmethanol-D2 is a deuterated aromatic alcohol, specifically the deuterated form of 2,6-difluorobenzyl alcohol, where the hydroxyl hydrogen is replaced by deuterium. This isotopic labeling is critical for applications requiring enhanced analytical precision and metabolic stability studies. It serves as a valuable synthetic intermediate and analytical standard for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly in the development of novel active ingredients and advanced material science.

Application

• Pharmaceutical Intermediate: Used in the synthesis of deuterated drug candidates for improved pharmacokinetic profiles (PK/PD studies) and as internal standards in bioanalytical methods (LC-MS/MS).
• Agrochemical Research: Serves as a building block for developing novel, isotopically labeled pesticides and herbicides to study environmental fate and degradation pathways.
• Metabolic Tracing: Acts as a probe in metabolic flux analysis and mechanistic studies due to the kinetic isotope effect (KIE) imparted by the deuterium label.
• NMR Spectroscopy: Employed as a solvent or chemical shift reference standard in nuclear magnetic resonance (NMR) spectroscopy for structural elucidation.
• Material Science: Utilized in the synthesis of specialty polymers and liquid crystals where deuterium incorporation modifies physical properties.
• Analytical Reference Standard: Provides a high-purity certified reference material (CRM) for quantitative analysis and method validation in regulatory environments.

Basic Information

Product Name	2,6-Difluorophenylmethanol-D2
CAS No.	1346601-28-2
Molecular Formula	C7H5D2F2O
Molecular Weight	145.13 g/mol
Synonyms	(2,6-Difluorophenyl)methanol-d2; 2,6-Difluorobenzyl Alcohol-d2; Deutero(2,6-difluorophenyl)methanol; α,α-Dideutero-2,6-difluorobenzyl Alcohol; (2,6-Difluorophenyl)methan-d2-ol; 2,6-Difluorobenzyl-α,α-d2 Alcohol; Benzyl-d2 Alcohol, 2,6-difluoro-
EINECS	Contact for details

Quality Control

Our 2,6-Difluorophenylmethanol-D2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC-MS, to ensure high chemical and isotopic purity and the absence of critical impurities. Certificates of Analysis (COA) detailing batch-specific results for identity, assay, deuterium enrichment, and related substances are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and potential isotopic exchange.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC / GC)	≥ 97.0%
Deuterium Enrichment (NMR / MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.