Description

n-[[4-[2-[Bis(Trideuteriomethyl)Amino]Ethoxy]Phenyl]Methyl]-3,4-Dimethoxybenzamide:Hydrochloride is a high-purity, deuterated chemical compound designed for advanced research and development applications. This compound is valued for its role as a stable isotope-labeled standard or intermediate, providing critical insights in analytical and metabolic studies. It is primarily utilized by pharmaceutical R&D teams, analytical laboratories, and specialty chemical manufacturers working on drug discovery, pharmacokinetics, and mass spectrometry.

Application

• Pharmaceutical Reference Standard: Used as a deuterium-labeled internal standard for the precise quantification of parent compounds in bioanalytical methods like LC-MS/MS.
• Metabolic Pathway Research: Serves as a tracer in drug metabolism and pharmacokinetics (DMPK) studies to investigate metabolic stability and identify metabolites.
• Active Pharmaceutical Ingredient (API) Intermediate: Acts as a key synthetic building block in the development of novel therapeutic agents.
• Proteomics & Biomarker Discovery: Employed in quantitative proteomics and biomarker validation assays to ensure accuracy and reproducibility.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme mechanisms and protein-ligand interactions.
• Regulatory & Quality Control: Supports method development and validation for regulatory submissions to agencies like the FDA and EMA.

Basic Information

Item	Details
Product Name	n-[[4-[2-[Bis(Trideuteriomethyl)Amino]Ethoxy]Phenyl]Methyl]-3,4-Dimethoxybenzamide:Hydrochloride
CAS No.	1346601-02-2
Molecular Formula	C21H28D6ClN2O4
Molecular Weight	Contact for details
Synonyms	Benzamide, N-[[4-[2-[bis(trideuteriomethyl)amino]ethoxy]phenyl]methyl]-3,4-dimethoxy-, hydrochloride; 3,4-Dimethoxy-N-({4-[2-(bis[(2H3)methyl]amino)ethoxy]phenyl}methyl)benzamide hydrochloride; Deuterated Benzamide Hydrochloride Derivative; (Trideuteriomethyl)amino Ethoxy Benzamide HCl; Labeled Internal Standard 1346601-02-2; D6-Labeled Benzamide Hydrochloride
EINECS	Contact for details

Quality Control

Our n-[[4-[2-[Bis(Trideuteriomethyl)Amino]Ethoxy]Phenyl]Methyl]-3,4-Dimethoxybenzamide:Hydrochloride is manufactured under strict quality systems to ensure batch-to-batch consistency and high isotopic purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, isotopic enrichment, and impurity profiles. We adhere to relevant ICH guidelines for analytical method validation to support its use in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Isotopic Purity (D6)	≥ 98.0 atom % D
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.