Description

α-Methyl-6-Benzofuran Ethanamine-D6 Hydrochloride is a high-purity, deuterium-labeled isotopologue of a key benzofuran ethanamine derivative, essential for advanced research and development. This compound serves as a critical internal standard and tracer in quantitative analytical methods, ensuring unparalleled accuracy and reliability in data. It is primarily utilized by pharmaceutical researchers, analytical chemists, and contract research organizations (CROs) engaged in pharmacokinetic studies, metabolic pathway analysis, and the development of novel therapeutic agents.

Application

• Internal Standard for LC-MS/MS: Essential for the precise quantification of the non-deuterated parent compound in complex biological matrices like plasma, serum, and tissue homogenates.
• Metabolic Studies: Used as a stable isotope tracer to investigate drug metabolism, identify metabolites, and elucidate biotransformation pathways.
• Pharmacokinetic/Pharmacodynamic (PK/PD) Research: Enables accurate measurement of drug absorption, distribution, metabolism, and excretion (ADME) parameters in preclinical and clinical studies.
• Method Development and Validation: A critical component in developing and validating robust, GLP-compliant bioanalytical assays for regulatory submissions.
• Isotope Dilution Mass Spectrometry (IDMS): Employed in high-precision analytical techniques to minimize matrix effects and improve measurement accuracy.
• Reference Material for Quality Control: Serves as a certified reference material in quality control laboratories to ensure the accuracy of analytical results.

Basic Information

Item	Details
Product Name	α-Methyl-6-Benzofuran Ethanamine-D6 Hydrochloride
CAS No.	1346600-35-8
Molecular Formula	C₁₁H₁₀D₆ClNO
Molecular Weight	Contact for details
Synonyms	6-(2-Aminopropyl)benzofuran-D6 hydrochloride; 1-(6-Benzofuranyl)-2-propanamine-D6 hydrochloride; 6-APB-D6 hydrochloride; 6-(2-Aminopropyl)benzofuran-d6 HCl; α-Methyl-1-benzofuran-6-ethanamine-D6 hydrochloride; Deuterated 6-APB HCl; 6-[(2-Amino-1,1,2,2,3,3-hexadeuteriopropyl)]benzofuran hydrochloride
EINECS	Contact for details

Quality Control

Every batch of α-Methyl-6-Benzofuran Ethanamine-D6 Hydrochloride is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical data to support its use in regulated environments. Certificates of Analysis (COA) are supplied with each shipment, detailing critical parameters including isotopic purity (D-enrichment), chemical purity, and identity confirmation via orthogonal methods. Our quality commitment ensures consistency and reliability for your most demanding research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert conditions (e.g., nitrogen or argon atmosphere) after opening to maintain stability and purity. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0% (Chemical Purity)
Isotopic Purity (D-enrichment)	≥98.0 atom % D
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.