Description

3-(4-Chlorophenyl-D4)-4-Hydroxybutyric Acid Sodium Salt is a high-purity, deuterium-labeled derivative of a key pharmaceutical intermediate. This compound is specifically designed for use in advanced research and development, offering a stable isotopic label for precise metabolic and pharmacokinetic studies. It is an essential material for scientists in pharmaceutical development, contract research organizations (CROs), and analytical laboratories working on drug discovery and bioanalytical method development.

Application

• Pharmaceutical R&D: Serves as a critical deuterated internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the quantitative analysis of its non-labeled counterpart in biological matrices.
• Metabolite Tracing: Used in drug metabolism and pharmacokinetics (DMPK) studies to track the fate of drug molecules and identify metabolites with high accuracy.
• Bioanalytical Method Development: Enables the development and validation of highly sensitive and specific analytical methods for preclinical and clinical studies.
• Stable Isotope Labeling: Acts as a building block for the synthesis of more complex deuterium-labeled compounds for use in mechanistic and environmental fate studies.
• Quality Control & Reference Standard: Provides a certified reference material for ensuring the accuracy and precision of analytical results in quality control laboratories.

Basic Information

Product Name	3-(4-Chlorophenyl-D4)-4-Hydroxybutyric Acid Sodium Salt
CAS No.	1346600-25-6
Molecular Formula	C10H7D4ClNaO3
Molecular Weight	237.66 g/mol (approx.)
Synonyms	Sodium 3-(4-Chlorophenyl-d4)-4-hydroxybutanoate; 4-Hydroxy-3-(4-chlorophenyl-d4)butyric Acid Sodium Salt; 3-(p-Chlorophenyl-d4)-4-hydroxybutyric Acid Sodium Salt; GHB-d4 (4-chlorophenyl analog) Sodium Salt; Deuterated Sodium 4-Hydroxy-3-(4-chlorophenyl)butyrate; [D4]-3-(4-Chlorophenyl)-4-hydroxybutyric Acid Sodium Salt; Sodium (4-Chlorophenyl-d4)-γ-hydroxybutyrate
EINECS	Contact for details

Quality Control

Every batch of 3-(4-Chlorophenyl-D4)-4-Hydroxybutyric Acid Sodium Salt is manufactured under strict quality management systems. The product undergoes comprehensive analytical testing, including NMR, HPLC, and MS, to confirm chemical identity, isotopic purity (deuterium enrichment), and chemical purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes to ensure it meets the stringent requirements for use as a reference standard in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.