Description

4-Amino-5-Chloro-2-Ethoxybenzoic Acid-D5 is a high-purity, deuterium-labeled analog of a key benzoic acid derivative, serving as a critical internal standard and reference material in advanced analytical chemistry. Its primary value lies in enabling precise quantification and method validation in complex matrices through mass spectrometry, ensuring data accuracy and regulatory compliance. This compound is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and forensic science industries, particularly for metabolism studies, pharmacokinetic analysis, and impurity profiling.

Application

• Internal Standard for LC-MS/MS: Used as a deuterated internal standard in quantitative bioanalysis for drug and metabolite quantification in biological fluids.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of process-related impurities and degradation products in active pharmaceutical ingredient (API) development.
• Metabolite Tracing & Pharmacokinetics: Facilitates stable isotope labeling studies to track drug metabolism and determine pharmacokinetic parameters.
• Forensic & Clinical Toxicology: Employed in confirmatory testing methods for the accurate detection of specific drug classes or their metabolites.
• Agrochemical Research: Supports environmental fate studies and residue analysis of related chemical compounds.
• Method Development & Validation: Critical for developing and validating robust, sensitive, and specific analytical methods in regulated environments.

Basic Information

Product Name	4-Amino-5-Chloro-2-Ethoxybenzoic Acid-D5
CAS No.	1346600-23-4
Molecular Formula	C9H4D5ClNO3
Molecular Weight	~230.68 g/mol
Synonyms	2-Ethoxy-4-amino-5-chlorobenzoic Acid-D5; 5-Chloro-4-amino-2-ethoxybenzoic Acid-D5; 4-Amino-5-chloro-2-ethoxy-d5-benzoic Acid; Deuterated 4-Amino-5-Chloro-2-Ethoxybenzoic Acid; 4-Amino-5-chloro-2-ethoxybenzoic-2,3,5,6-d4-acid-d; Benzoic acid, 4-amino-5-chloro-2-ethoxy-, pentadeuterio-; (Internal Standard for Mosapride related compounds)
EINECS	Contact for details

Quality Control

Our 4-Amino-5-Chloro-2-Ethoxybenzoic Acid-D5 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR and mass spectrometry, to confirm isotopic purity and chemical identity, and HPLC to determine chemical purity. We provide comprehensive Certificates of Analysis (COA) detailing all specifications, including deuterium incorporation levels. Our quality commitment ensures the material meets the stringent requirements for use as a certified reference standard in GLP and ISO 17025 accredited laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (Deuterium Incorporation)	≥98 atom % D
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.