Description

4-Chloro Perazine-D8 is a deuterium-labeled analog of 4-Chloro Perazine, a compound of significant interest in pharmaceutical research and development. This stable isotope-labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring high accuracy and precision in analytical measurements. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, contract research organization (CRO), and academic sectors for drug metabolism and pharmacokinetics (DMPK) studies, bioanalytical method development, and forensic analysis.

Application

• Internal Standard for LC-MS/MS: Serves as a critical reference compound in liquid chromatography-tandem mass spectrometry for the accurate quantification of 4-Chloro Perazine in complex biological matrices like plasma, serum, and urine.
• Drug Metabolism Studies (DMPK): Used in pharmacokinetic and pharmacodynamic research to trace and measure the parent drug and its metabolites, aiding in understanding absorption, distribution, metabolism, and excretion (ADME).
• Bioanalytical Method Development and Validation: Essential for developing and validating robust, sensitive, and specific analytical methods in compliance with regulatory guidelines (e.g., FDA, EMA).
• Forensic and Clinical Toxicology: Employed in the precise detection and quantification of psychoactive substances for forensic investigations and clinical diagnostic purposes.
• Pharmaceutical Quality Control (QC): Supports impurity profiling and stability testing of active pharmaceutical ingredients (APIs) and finished drug products.
• Isotope Dilution Mass Spectrometry (IDMS): Applied in this gold-standard technique for achieving the highest level of measurement accuracy in quantitative analysis.

Basic Information

Product Name	4-Chloro Perazine-D8
CAS No.	1346600-16-5
Molecular Formula	C₁₉H₁₃D₈ClN₂S
Molecular Weight	~348.94 g/mol
Synonyms	4-Chloroperazine-d8; Deuterated 4-Chloro Perazine; 4-Chloro-N,N-dimethyl-10H-phenothiazine-10-ethanamine-d8; 4-CP-d8; Perazine-4-chloro-d8; 10-[2-(Dimethylamino-d6)ethyl]-4-chlorophenothiazine-d2; 4-Chloroperazine (phenyl-d5, ethyl-d3); LS-183087-d8
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro Perazine-D8 is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive testing performed using advanced techniques including NMR (¹H, ¹³C), HPLC, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming batch-specific data for identity, purity (by HPLC), isotopic enrichment, and residual solvents, ensuring compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.