Description

Acetylsulfamonomethoxine-D4 is a deuterium-labeled internal standard critical for ensuring analytical accuracy in quantitative mass spectrometry. This stable isotope-labeled compound is essential for precise quantification and method validation in regulated environments. It is primarily used by analytical laboratories and research institutions in the pharmaceutical, veterinary medicine, and environmental monitoring sectors for the accurate analysis of sulfonamide antibiotics.

Application

• Internal Standard for LC-MS/MS: Used as a quantitative reference standard in liquid chromatography-tandem mass spectrometry for analyzing sulfamonomethoxine and related metabolites.
• Pharmaceutical Research & Development: Enables accurate pharmacokinetic and metabolic studies of sulfonamide drugs in preclinical and clinical research.
• Veterinary Drug Residue Analysis: Critical for compliance testing in food safety, ensuring accurate measurement of sulfamonomethoxine residues in animal-derived products (meat, milk, eggs).
• Environmental Monitoring: Supports the trace analysis of antibiotic pollutants in water and soil samples.
• Method Development & Validation: Serves as a key component in developing and validating robust, regulatory-compliant analytical methods (following FDA, EMA guidelines).
• Quality Control in Manufacturing: Used in the quality control laboratories of API manufacturers to monitor process impurities and ensure batch consistency.

Basic Information

Product Name	Acetylsulfamonomethoxine-D4
CAS No.	1346600-08-5
Molecular Formula	C13H10D4N4O4S
Molecular Weight	314.36 g/mol (for deuterated form)
Synonyms	N4-Acetylsulfamonomethoxine-d4; Sulfamonomethoxine-d4 Acetate; 4-Amino-N-(6-methoxy-4-pyrimidinyl)benzenesulfonamide-d4 Acetamide; Deuterated Sulfamonomethoxine Acetate; [2H4]-Acetylsulfamonomethoxine; ASMM-d4; Internal Standard for Sulfamonomethoxine
EINECS	Contact for details

Quality Control

Every batch of Acetylsulfamonomethoxine-D4 is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity to meet the exacting demands of quantitative analysis. Comprehensive testing includes assay (by HPLC), isotopic enrichment (by MS), and identification (by IR and/or NMR). A detailed Certificate of Analysis (COA) providing batch-specific data is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Chemical Purity (HPLC)	≥ 95.0% (by area normalization)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.