Description

n-tert-Butyloxycarbonyl Dl-Alaninol Methyl Ether-D3 is a deuterium-labeled derivative of a protected amino alcohol, serving as a crucial isotopically labeled building block in advanced chemical synthesis. Its core value lies in enabling precise metabolic and pharmacokinetic studies through the incorporation of stable isotopes. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors who require high-purity labeled intermediates for tracer studies, analytical method development, and the synthesis of novel active compounds.

Application

• Pharmaceutical Research: As a deuterium-labeled intermediate for the synthesis of isotopically labeled Active Pharmaceutical Ingredients (APIs) for drug metabolism and pharmacokinetics (DMPK) studies.
• Metabolic Tracer Development: Used in the creation of internal standards for Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) to ensure accurate quantitative bioanalysis.
• Mechanistic Studies: Employed in chemical and biochemical research to investigate reaction mechanisms and metabolic pathways using isotope effects.
• Agrochemical Development: As a building block for synthesizing labeled analogs of pesticides or herbicides to study environmental fate and degradation.
• Peptidomimetic Synthesis: Utilized in medicinal chemistry for the preparation of modified peptide structures where the deuterated alaninol moiety is incorporated.
• Academic & Contract Research: Serves as a specialized reagent in university laboratories and CROs (Contract Research Organizations) focused on isotopic chemistry.

Basic Information

Product Name	n-tert-Butyloxycarbonyl Dl-Alaninol Methyl Ether-D3
CAS No.	1346600-07-4
Molecular Formula	C10H18D3NO4
Molecular Weight	219.30 g/mol (approx.)
Synonyms	Boc-DL-Alaninol Methyl Ether-d3; (±)-2-[(tert-Butoxycarbonyl)amino]propan-1-ol Methyl Ether-d3; DL-2-((tert-Butoxycarbonyl)amino)-1-methoxypropane-d3; N-Boc-DL-alaninol methyl ether-d3; tert-Butyl (1-methoxy-1-deuterio-2-propanyl)carbamate-d2; (RS)-N-(tert-Butoxycarbonyl)-1-methoxy-2-propanamine-d3; Deuterated Boc-Alaninol Methyl Ether
EINECS	Contact for details

Quality Control

Our n-tert-Butyloxycarbonyl Dl-Alaninol Methyl Ether-D3 is produced under controlled conditions to ensure high isotopic and chemical purity, critical for research integrity. Each batch undergoes rigorous analytical testing, including NMR (Nuclear Magnetic Resonance) for deuterium incorporation verification and HPLC (High-Performance Liquid Chromatography) for chemical purity assessment. Certificates of Analysis (COA) detailing isotopic purity (D%), chemical purity, and specific analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage, consider keeping the material under an inert atmosphere (e.g., nitrogen or argon) in a freezer (-20°C) to maximize stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Isotopic Purity (D%)	≥ 98 atom % D
Chemical Purity (by GC or HPLC)	≥ 97%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.