Description

(Rs)-1-[3-(Methylamino)-1-(2-Thienyl)Propyl]-2-Naphthalenol CAS NO 1346599-09-4 is a chiral naphthol derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate or a potential active pharmaceutical ingredient (API) precursor, valued for its unique molecular architecture combining a naphthalene core with thiophene and methylamino functional groups. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel therapeutic agents, particularly within central nervous system (CNS) and receptor-targeted drug programs.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of complex drug candidates.
• Chiral Synthesis: Used in asymmetric synthesis and resolution processes to produce enantiomerically pure compounds.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Reference Standard: Employed as an analytical standard for quality control and method development in API manufacturing.
• Biochemical Research: Potential use as a ligand or probe in biochemical assays and receptor binding studies.
• Process Development: Used in scaling up synthetic routes from laboratory to pilot plant scale.

Basic Information

Product Name	(Rs)-1-[3-(Methylamino)-1-(2-Thienyl)Propyl]-2-Naphthalenol
CAS No.	1346599-09-4
Molecular Formula	C19H21NOS
Molecular Weight	311.44 g/mol
Synonyms	1-[(1RS)-3-(Methylamino)-1-(2-thienyl)propyl]-2-naphthalenol; (RS)-1-[3-(Methylamino)-1-(thiophen-2-yl)propyl]naphthalen-2-ol; 2-Naphthalenol, 1-[3-(methylamino)-1-(2-thienyl)propyl]-, (RS)-; (R,S)-1-(3-(Methylamino)-1-(thiophen-2-yl)propyl)naphthalen-2-ol; (RS)-N-Methyl-1-(2-naphthyl)-3-(2-thienyl)propan-1-amine; (RS)-1-(3-(Methylamino)-1-(thien-2-yl)propyl)-2-naphthol
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized and controlled using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive (store away from light). For long-term storage, consider storage under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.