Description

2-Bromo-1,3-Propanediol-D4 is a deuterium-labeled analog of 2-bromo-1,3-propanediol, a valuable building block in synthetic organic chemistry. This stable isotope-labeled compound is essential for applications requiring precise tracking and analysis, such as in metabolic studies and as an internal standard for mass spectrometry. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors for the development and quality control of deuterated active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Deuterated Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of deuterium-labeled drugs, where the incorporation of deuterium can improve metabolic stability and pharmacokinetic profiles.
• Mass Spectrometry Internal Standard: Used as a high-purity internal standard for the accurate quantification of its non-deuterated counterpart or related metabolites in bioanalytical assays (LC-MS, GC-MS).
• Metabolic Pathway Tracing: Enables detailed investigation of biochemical pathways and drug metabolism in pharmacological and toxicological research.
• NMR Spectroscopy: Acts as a useful probe or starting material in nuclear magnetic resonance (NMR) studies due to the distinct spectroscopic properties of deuterium.
• Agrochemical Research: Employed in the development and analysis of novel deuterated pesticides and herbicides.
• Fine Chemical Synthesis: Functions as a specialized reagent for introducing deuterated moieties into complex organic molecules for material science and chemical biology.

Basic Information

Product Name	2-Bromo-1,3-Propanediol-D4
CAS No.	1346598-67-1
Molecular Formula	C3D4H2BrO2
Molecular Weight	154.99 g/mol (approx.)
Synonyms	2-Bromo-1,3-propanediol-d4; 2-Bromopropane-1,3-diol-d4; 1,3-Propanediol, 2-bromo-, tetradeuterio-; Deuterated 2-Bromo-1,3-propanediol; [D4]-2-Bromo-1,3-propanediol; 2-Bromo-1,3-dihydroxypropane-d4; (2-Bromo-1,3-propanediol)-d4
EINECS	Contact for details

Quality Control

Our 2-Bromo-1,3-Propanediol-D4 is manufactured under strict quality systems to ensure high isotopic purity and chemical integrity, meeting the stringent requirements of research and development. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (D-atom %), chemical purity (by HPLC/GC), and identity confirmation (by NMR, MS). We adhere to relevant guidelines for the production of stable isotope-labeled compounds.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Isotopic Purity (D-atom %)	≥ 98%
Chemical Purity (HPLC/GC)	≥ 97%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.