Description

n-(2,6-Dimethylphenyl)-1-(Trideuteriomethyl)Piperidine-2-Carboxamide is a deuterated organic compound of significant interest in advanced pharmaceutical research and development. Its core value lies in its role as a stable isotope-labeled analog, which is essential for conducting precise metabolic, pharmacokinetic, and bioanalytical studies. This high-purity compound is primarily needed by pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in drug discovery and development, particularly for creating internal standards in mass spectrometry.

Application

• As a deuterium-labeled internal standard for the accurate quantification of its non-deuterated counterpart in bioanalytical methods using LC-MS/MS.
• In pharmacokinetic (PK) and metabolism studies to trace drug absorption, distribution, metabolism, and excretion (ADME) without isotopic interference.
• For drug discovery and development programs, enabling more reliable and sensitive analytical data to support regulatory filings.
• Use in academic and industrial research investigating the biological activity and degradation pathways of piperidine carboxamide derivatives.
• As a high-purity reference material for quality control and method validation in analytical laboratories.

Basic Information

Product Name	n-(2,6-Dimethylphenyl)-1-(Trideuteriomethyl)Piperidine-2-Carboxamide
CAS No.	1346597-90-7
Molecular Formula	C16H23D3N2O
Molecular Weight	265.41 g/mol
Synonyms	1-(Trideuteriomethyl)-N-(2,6-dimethylphenyl)piperidine-2-carboxamide; N-(2,6-Dimethylphenyl)-1-(trideuteromethyl)-2-piperidinecarboxamide; Deuterated Lidocaine Derivative; d3-Lidocaine Amide Analog; 2,6-Dimethylacetanilide Deuterated Piperidine Derivative; (2,6-Xylyl)carbamoyl Deuterated Piperidine; 1-(CD3)-N-(2,6-Dimethylphenyl)piperidine-2-carboxamide
EINECS	Contact for details

Quality Control

Our n-(2,6-Dimethylphenyl)-1-(Trideuteriomethyl)Piperidine-2-Carboxamide is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for sensitive analytical applications. Each batch undergoes comprehensive analysis, including assay by HPLC, determination of deuterium incorporation by NMR or MS, and control of related substances. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and compliance with your research standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect this light-sensitive material from prolonged exposure.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Incorporation (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.