Description

4-(4-Chlorophenyl)-2,6-Piperidinedione-D4 is a deuterated analog of a key piperidinedione derivative, where four hydrogen atoms are replaced with deuterium, serving as a stable isotope-labeled internal standard. This high-purity compound is critical for ensuring the accuracy and reliability of quantitative analysis in complex matrices, particularly in pharmacokinetic and metabolic studies. It is an essential tool for researchers and quality control laboratories in the pharmaceutical and analytical chemistry sectors who require precise measurement of the parent compound.

Application

• Primary use as a stable isotope-labeled internal standard for Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) analysis.
• Quantification of the non-deuterated parent compound in bioanalytical studies, including drug metabolism and pharmacokinetics (DMPK).
• Method development and validation in pharmaceutical research to meet regulatory requirements for assay precision.
• Use in environmental testing for tracing and quantifying specific chemical residues.
• Application in clinical diagnostics for accurate biomarker measurement.
• Supporting academic research involving the mechanistic study of related compounds.

Basic Information

Product Name	4-(4-Chlorophenyl)-2,6-Piperidinedione-D4
CAS No.	1346597-83-8
Molecular Formula	C11H5D4ClNO2
Molecular Weight	226.68 g/mol (for D4 isotopologue)
Synonyms	4-(4-Chlorophenyl)piperidine-2,6-dione-d4; 4-(p-Chlorophenyl)-2,6-piperidinedione-d4; 2,6-Dioxo-4-(4-chlorophenyl)piperidine-d4; Deuterated 4-(4-Chlorophenyl)glutarimide; 4-(4-Chlorophenyl)-2,6-dioxopiperidine-d4; Aminoglutethimide Impurity D-d4 (related compound); Stable Isotope Labeled Internal Standard for Aminoglutethimide analogs
EINECS	Contact for details

Quality Control

Every batch of 4-(4-Chlorophenyl)-2,6-Piperidinedione-D4 is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity, verified by advanced analytical techniques including NMR, HPLC, and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and impurity profile is provided with each shipment to ensure it meets the stringent requirements for analytical reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term stability, consider storage under inert atmosphere. Keep the container sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.