Description

(1-Oxo-2,3-Dihydro-1H-Isoindol-5-Yl)Boronic Acid is a high-value boronic acid derivative and a key synthetic building block in modern organic chemistry. Its primary commercial value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those containing the isoindolinone scaffold, which is prevalent in compounds with neurological and oncological activity.
• Agrochemical Synthesis: Used to construct complex molecules for the development of new pesticides, herbicides, and fungicides with improved efficacy and selectivity.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics, due to its conjugated structure.
• Chemical Biology & Probe Development: Employed in the design and synthesis of molecular probes and inhibitors for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CROs/CMOs producing specialized, high-value compounds for client projects.
• Academic & Industrial R&D: Fundamental reagent in research laboratories for methodological development in cross-coupling chemistry and heterocyclic compound synthesis.

Basic Information

Product Name	(1-Oxo-2,3-Dihydro-1H-Isoindol-5-Yl)Boronic Acid
CAS No.	1346526-56-4
Molecular Formula	C8H8BNO3
Molecular Weight	176.97 g/mol
Synonyms	5-Isoindolinoneboronic Acid; 5-Borono-1,3-dihydro-2H-isoindol-1-one; 1,3-Dihydro-1-oxo-2H-isoindole-5-boronic Acid; (1-Oxo-1,3-dihydro-2H-isoindol-5-yl)boronic Acid; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isoindolin-1-one (protected form); B-(1-Oxo-2,3-dihydro-1H-isoindol-5-yl)boronic Acid; 2H-Isoindol-1-one, 5-borono-1,3-dihydro-
EINECS	Contact for details

Quality Control

Our (1-Oxo-2,3-Dihydro-1H-Isoindol-5-Yl)Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, which is critical for sensitive cross-coupling reactions. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP and ISO 9001 compliant manufacturing for advanced applications, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%
Solubility	Soluble in common polar organic solvents (e.g., DMF, DMSO)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.