Description

tert-Butyl 3-Bromo-2-formyl-1H-indole-1-carboxylate is a high-value, multi-functional indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a protected, reactive scaffold for constructing complex heterocyclic molecules, enabling efficient and selective chemical transformations. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and explore new chemical spaces.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and CNS (Central Nervous System) therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the indole core's bioactivity.
• Material Science: Serves as a precursor for organic semiconductors and functional dyes due to its conjugated indole structure.
• Academic & Contract Research: A valuable reagent for methodological studies in cross-coupling reactions, palladium-catalyzed transformations, and heterocyclic chemistry.
• Chemical Library Synthesis: Employed in combinatorial and parallel synthesis to create diverse compound libraries for high-throughput screening.

Basic Information

Product Name	tert-Butyl 3-Bromo-2-formyl-1H-indole-1-carboxylate
CAS No.	1346156-91-9
Molecular Formula	C14H14BrNO3
Molecular Weight	324.17 g/mol
Synonyms	1-Boc-3-bromo-2-formylindole; tert-Butyl 3-bromo-2-formylindole-1-carboxylate; 3-Bromo-1-[(tert-butoxy)carbonyl]-1H-indole-2-carboxaldehyde; 1H-Indole-1-carboxylic acid, 3-bromo-2-formyl-, 1,1-dimethylethyl ester; Boc-3-bromo-2-formylindole; 3-Bromo-2-formylindole-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Bromo-2-formyl-1H-indole-1-carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, NMR for structural confirmation, and mass spectrometry. A detailed Certificate of Analysis (COA) documenting identity, purity, and all relevant specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry, and well-ventilated place. Allow the container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.