Description

Cholesterol 3-Acetate-D7 is a high-purity, deuterium-labeled derivative of cholesterol acetate, serving as a critical internal standard for precise quantitative analysis in mass spectrometry. This compound is essential for researchers and quality control laboratories requiring the highest level of accuracy in lipidomic and metabolic studies. It is primarily utilized in pharmaceutical research, clinical diagnostics, and analytical chemistry for method development and validation.

Application

• Internal Standard for LC-MS/MS: Used as a deuterated internal standard for the accurate quantification of cholesterol and its esters in complex biological matrices like plasma, serum, and tissues.
• Metabolic Pathway Tracing: Employed in stable isotope labeling studies to investigate cholesterol biosynthesis, absorption, and turnover rates.
• Pharmaceutical R&D: Critical for the bioanalysis of drug candidates targeting lipid metabolism, enabling precise pharmacokinetic and pharmacodynamic studies.
• Clinical Diagnostics: Supports the development and validation of high-throughput clinical assays for measuring cholesterol-related biomarkers.
• Food and Nutraceutical Analysis: Applied in the accurate determination of sterol content in fortified foods, dietary supplements, and edible oils.
• Quality Control Reference: Serves as a certified reference material (CRM) for calibrating analytical instruments and ensuring data integrity in regulated laboratories.

Basic Information

Product Name	Cholesterol 3-Acetate-D7
CAS No.	1345629-08-4
Molecular Formula	C29H41D7O2
Molecular Weight	~435.7 g/mol
Synonyms	Cholest-5-en-3β-ol 3-Acetate-d7; (3β)-Cholest-5-en-3-yl Acetate-d7; Deuterated Cholesterol Acetate; Cholesterol-d7 Acetate; 3β-Acetoxycholest-5-ene-d7; 5-Cholesten-3β-ol Acetate-d7; Cholesteryl-d7 Acetate
EINECS	Contact for details

Quality Control

Our Cholesterol 3-Acetate-D7 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and MS, to confirm chemical identity, isotopic purity (D-enrichment), and chemical purity. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. For long-term storage, consider keeping the product at -20°C under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Chemical Purity (NMR)	Conforms
Solubility	Soluble in chloroform, DMSO; slightly soluble in ethanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.