Description

(R)-1-(3-Fluoro-4-Methylphenyl)Ethanol is a high-purity chiral intermediate of significant importance in modern synthetic chemistry. Its value lies in its role as a key building block for the enantioselective synthesis of complex molecules, particularly in the pharmaceutical sector. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials where stereochemical purity is critical.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and production of enantiomerically pure drugs, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced, stereoselective pesticides and herbicides where the specific (R)-enantiomer activity is required.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that demand high enantiomeric excess (ee).
• Academic and R&D: A valuable compound for methodological development in organic chemistry and medicinal chemistry research within university and corporate laboratories.
• Material Science: Potential building block for chiral polymers and liquid crystals with specific optical properties.

Basic Information

Product Name	(R)-1-(3-Fluoro-4-Methylphenyl)Ethanol
CAS No.	1344955-38-9
Molecular Formula	C9H11FO
Molecular Weight	154.18 g/mol
Synonyms	(R)-1-(3-Fluoro-4-methylphenyl)ethan-1-ol; (R)-α-Methyl-3-fluoro-4-methylbenzyl alcohol; (R)-1-(3-Fluoro-p-tolyl)ethanol; (R)-3-Fluoro-4-methyl-α-methylbenzyl alcohol; (R)-1-(3-Fluoro-4-methylphenyl)ethyl alcohol; (R)-FMPE; (R)-FMPEA; (R)-FMPE-OH
EINECS	Contact for details

Quality Control

Our (R)-1-(3-Fluoro-4-Methylphenyl)Ethanol is produced under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral HPLC to confirm high enantiomeric purity, and NMR/IR for structural verification. We provide Certificates of Analysis (COA) with detailed specifications for purity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.